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. 2017 Feb 15;13(4):1360–1368. doi: 10.3892/etm.2017.4128

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — ICA inhibits the expression of N1ICD protein. Rat femora were subjected to cell lysis to extract proteins. Expression of GAPDH and N1ICD protein was detected by (A) western blot and (B) quantified. Compared with the sham-operated group, expression of N1ICD increased in the OVX-NT group. Compared with the OVX-NT group, expression of N1ICD decreased in the ICA-M group. **P<0.01 vs. the sham group; ^∆∆P<0.01 vs. the OVX group. OVX-NT, ovariectomized-no treatment group; ICA-M, medium-dose icarrin group; N1ICD, Notch1 intracellular domain.