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. 2017 Apr 3;7:45684. doi: 10.1038/srep45684

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Copyright © 2017, The Author(s)

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(a) curves of 5D model with and . For , the value of dendritic input is and . For , they are and . (b) Dendritic voltage V_D and associated Ca²⁺ current I_Ca for each value of . The value of I_S and I_D are indicated in each plot. (c) Dendritic Ca²⁺ spike is evoked by the interactions between the back-propagating APs and the excitatory inputs received by apical dendrites. The Ca²⁺ spike induced by back-propagating APs is also referred to as BAC firing, which can be propagated to soma to modulate the output APs.

Inline graphic — (a) curves of 5D model with and . For , the value of dendritic input is and . For , they are and . (b) Dendritic voltage V_D and associated Ca²⁺ current I_Ca for each value of . The value of I_S and I_D are indicated in each plot. (c) Dendritic Ca²⁺ spike is evoked by the interactions between the back-propagating APs and the excitatory inputs received by apical dendrites. The Ca²⁺ spike induced by back-propagating APs is also referred to as BAC firing, which can be propagated to soma to modulate the output APs.