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. 2017 Apr 3;7:45684. doi: 10.1038/srep45684

Figure 7. Somatic APs and initiating dynamics evoked by pulse injected at dendritic chamber.

Figure 7

(a) Sample responses of the 5D model triggered by pulse input ID in the cases of Inline graphic. Somatic voltage VS, dendritic voltage VD, dendritic Ca2+ current ICa, internal current IDS, and instantaneous firing rate finst are plotted against time. The amplitude of ID is Inline graphic and its duration is 20 ms. (b) Plot of K+ activation variable w against time with Inline graphic. The spike train recorded in soma is also plotted in Inline graphic space. Five color lines in panel (a) and (b) indicate the times at which the nullclines are calculated. (c) Two-dimensional phase portraits in Inline graphic plane. The VS- and w-nullclines are respectively calculated at time point t1 − t5 indicated by colored lines in (a) and (b). Blue dotted line represents w-nullcline, and the inverted N-shape lines are the VS-nullclines at corresponding time point. Gray solid line is the VS trajectory, and black arrows indicate its direction. ‘S’ indicates stable fixed point, and ‘U’ indicates unstable fixed point. Somatic injection is Inline graphic.