Table III.

Right femur weights in sham-operated or OVX ddY mice.

	Absolute weight (g)			Relative weight (% of body weight)
Groups	Wet	Dry	Ash	Wet	Dry	Ash
Controls
Sham	0.094±0.006	0.065±0.004	0.039±0.003	0.327±0.025	0.229±0.024	0.137±0.019
OVX	0.089±0.007	0.051±0.003a	0.026±0.003a	0.205±0.010b	0.118±0.010a	0.059±0.007a
Estradiol	0.095±0.010	0.059±0.003a,c	0.034±0.004a,c	0.273±0.038b,e	0.170±0.012a,c	0.098±0.013a,c
PCS
1 ml/kg	0.091±0.005	0.054±0.003a,d	0.032±0.004a,c	0.240±0.010b,e	0.145±0.012a,c	0.086±0.011a,c
2 ml/kg	0.095±0.008	0.056±0.003a,c	0.033±0.004a,c	0.263±0.024b,e	0.156±0.017a,c	0.091±0.009a,c
4 ml/kg	0.092±0.007	0.056±0.004a,c	0.033±0.003a,c	0.261±0.043b,e	0.158±0.020a,c	0.093±0.013a,c

Values are expressed mean ± standard deviation (n=8).

^aP<0.01 vs. sham control by LSD test.

^bP<0.01 vs. sham control by MW test.

^cP<0.01

^dP<0.05 vs. OVX control by least significant difference test.

^eP<0.01 vs. OVX control by MW test. Three different dosages of PCS were orally administered, and 17β-estradiol was subcutaneously injected at a dose of 0.03 µg/head on the dorsal back skins, once a day for 84 days from 28 days after OVX surgery. OVX, bilateral ovariectomy; PCS, pomegranate concentrated solution; MW, Mann-Whitney U.