Figure 1. Virus injection via the posterior semicircular canal in the adult mouse does not cause permanent threshold shifts or cochlear damage.

(A,B) Cochlear thresholds, measured by DPOAEs or ABRs (group means ± SEMs) 2 wks after injection. (C,D) Outer and inner hair cell loss (group means ± SEMs) for each group, as seen immediately after the cochlear function measures in (A,B). Group sizes for (A,B) were: Normal = 5; AAV-EGFP = 5. Group sizes for (C,D) were the same except Normal = 3. Symbol key in (D) applies to all panels.