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. 2017 Apr 3;7:45895. doi: 10.1038/srep45895

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(A) western blot showed the protein expression of TM4SF1 and DDR1. The upregulation of DDR1 expression attenuated the loss of DDR1 expression after TM4SF1 silenced. (B) Transwell assays showed that upregulating the expression of DDR1 rescued the inhibitory effects of migration and invasion after decreasing the expression of TM4SF1.*P < 0.05. (a) siCtrl + pcDNA3.1(+)-vector (b) siTM4SF1+pcDNA3.1 (+) -vector (c) siTM4SF1 + pcDNA3.1(+)-DDR1.