TABLE 1.
Phage | Date of isolation | Position and mutation relative to ΦM1 wta | Effect on forward reading frameb: |
||
---|---|---|---|---|---|
F1 | F2 | F3 | |||
ΦM1-A | March 2007 | 15416, A to C | Y to S | T to P | No change |
ΦM1-B | March 2007 | 15292, C to T | R to stop | No change | P to L |
ΦM1-C | March 2007 | 15170, T to C | M to T | Stop to S | No change |
ΦM1-D | March 2007 | 15410, T to C | M to T | W to R | No change |
ΦM1-O | June 2009 | 15407, A to C | Q to P | No change | No change |
ΦM1-V | May 2009 | 15415, T to G | Y to D | No change | V to G |
ΦM1-W | May 2009 | 15398, A to T | D to V | M to L | Stop to C |
ΦM1-X | May 2009 | 15288, AA to A | FS to stop after 9 aa (wild-type F1 continues phiM1-23) | FS causing Q to H and stop after 3 aa (wild-type F2 stops after 9 aa) | FS causing N to T and shift of ORF1 into ORF2 (wild-type F3 stops after 3 aa) |
ΦM1-Y | May 2009 | 15397, G to A | |||
ΦM1-Z | May 2009 | 15416, A to G (cf. ΦM1-A) |
Mutations are indicated as, e.g., Y to S.
FS, frameshift; aa, amino acid.