Table I.
Myocardial enzyme changes prior to ischemia (n=15 rats per group; mean ± standard deviation).
| Index/ group | Prior to ischemia | Reperfusion for 10 min | Reperfusion for 30 min |
|---|---|---|---|
| LDH, U/l | |||
| Control | 9.3±1.2 | 9.2±1.1 | 9.0±1.5 |
| Ischemia | 9.1±2.1 | 29.7±8.3 | 20.6±8.0 |
| Remifentanil | 9.2±1.8 | 15.3±7.1a | 13.2±6.8a |
| Naloxone | 8.8±1.5 | 25.6±8.1 | 19.8±7.5 |
| Remifentanil + naloxone | 8.9±1.7 | 26.4±6.9 | 21.4±7.1 |
| CK-MB, U/l | |||
| Control | 1.8±0.5 | 1.7±1.0 | 1.7±0.7 |
| Ischemia | 2.1±0.7 | 5.8±1.5 | 3.4±1.2 |
| Remifentanil | 2.2±0.8 | 6.1±2.0 | 4.0±2.0 |
| Naloxone | 2.0±0.4 | 6.0±1.4 | 3.6±2.2 |
| Remifentanil + naloxone | 1.9±0.3 | 6.7±2.1 | 3.7±1.3 |
a
P<0.05 vs. the ischemic control group. LDH, lactate dehydrogenase; CK-MB, phosphocreatine kinase.