Figure 1. Species-dependent distribution of FUT1/FUT2/SEC1 α1,2-fucosyltransferase genes and ABO/GBGT1/A3GALT2/GGTA1/GLT6D1 α1,3-Gal(NAc) transferase genes.
This table shows the distribution of α1,2-FT genes and α1,3-Gal(NAc)T genes in a variety of organisms. Ensembl gene identifiers are listed only with the meaningful digits, excluding 0 s on the left from their IDs. Genes were categorized into groups based on Ensembl gene trees, chromosomal locations, and our own analyses, and they are aligned in different columns and shown highlighted in different colors. Amino acid sequences corresponding to the codons 266–268 of human A/B transferases are also shown. The symbol “---” indicates the absence of sequence motif, and “N/A” means not annotated in databases. A single column of “Pseudo/Ancient” was used to list two types of annotated gene sequences: The ABO retropseudogene sequences that were originally derived from an intronless cDNA are highlighted in tan color (Pseudo) and the sequences that formed a cluster next to the ABO gene in the phylogenetic analysis are highlighted in yellow (Ancient). The gene sequences that formed a cluster outside of the ABO/GBGT1 genes are highlighted in orange, and they are shown separately in the “ABO/GBGT1 Ancient” column. The annotated genes may or may not be functional, the latter of which may also be called as O genes or pseudogenes. Note that genome sequences were not complete for many species, and therefore, errors may exist. In addition, there are numerous homologous sequences that have yet to be annotated and mapped on chromosomes. Furthermore, polymorphism may also exist.