Table 2. Pathological grading of hepatic rejection.

Portal Inflammation	0	None
	1	Mostly lymphocytic inflammation involving, but not noticeably expanding, a minority of the triads
	2	Expansion of most or all of the triads, by a mixed infiltrate containing lymphocytes with occasional blasts, neutrophils and eosinophils
	3	Marked expansion of most or all of the triads by a mixed infiltrate containing numerous blasts and eosinophils with inflammatory spillover into the periportal parenchyma
Bile Duct Inflammation Damage	0	None
	1	A minority of the ducts are cuffed and infiltrated by inflammatory cells and show only mild reactive changes such as increased nuclear, cytoplasmic ratio of the epithelial cells
	2	Most or all of the ducts infiltrated by inflammatory cells. More than an occasional duct shows degenerative changes such as nuclear pleomorphism, disordered polarity and cytoplasmic vacuolization of the epithelium
	3	As above for 2, with most or all of the ducts showing degenerative changes or focal lumenal disruption
Venous Endothelial Inflammation	0	None
	1	Subendothelial lymphocytic infiltration involving some, but not a majority of the portal and/or hepatic venules
	2	Subendothelial infiltration involving most or all of the portal and/or hepatic venules
	3	As above for 2, with moderate or severe perivenular inflammation that extends into the perivenular parenchyma and is associated with perivenular hepatocyte necrosis