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Metabolic turnover analysis of the liver and skeletal muscle in C57 and ob/ob mice. A and B, [13C6]glucose-derived constitutive metabolites of the TCA cycle, pyruvate and glutamate of the liver (A) and skeletal muscle (B), in C57 and ob/ob mice. The level of each M+2 isotopomer in C57 mice was set at 1. Data are mean ± S.E. *, p < 0.05; **, p < 0.01; C57 versus ob/ob mice at the same time after [13C6]glucose administration.
