TABLE 2.
Geographic distribution of highly penicillin-susceptible (MIC, ≤0.12), relatively penicillin-resistant (MIC, >0.12 to <0.5), and penicillin-resistant (MIC, ≥0.5) isolates (American Heart Association endocarditis treatment categories) of G. adiacens and A. defectiva
| U.S. census region | % (no.) of G. adiacens isolates |
% (no.) of A. defectiva isolates |
||||
|---|---|---|---|---|---|---|
| Highly penicillin susceptible | Relatively penicillin resistant | Penicillin resistant | Highly penicillin susceptible | Relatively penicillin resistant | Penicillin resistant | |
| Midwest | 30.8 (32)a | 24 (25) | 45.2 (47) | 5.9 (2) | 8.8 (3) | 85.3 (29) |
| South | 37.6 (41)b | 15.6 (17) | 46.8 (51)b | 12.5 (4) | 3.1 (1) | 84.4 (27) |
| Northeast | 57.5 (23) | 15 (6) | 27.5 (11) | 21.1 (4) | 78.9 (15) | |
| West | 41.6 (72) | 22.5 (39) | 35.8 (62) | 16.4 (11) | 6 (4) | 77.6 (52) |
a
P value shows significant differences (P < 0.05) in isolate susceptibility between Midwest and Northeast.
b
P value shows significant differences (P < 0.05) in isolate susceptibility between South and Northeast.