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. 2017 Apr 3;7:45833. doi: 10.1038/srep45833

Table 3. Numbers of cumulative major and minor cardiovascular events in patients with intermittent claudication during the prospective follow-up, shown for the first 5 years and the entire follow-up time.

  First 5 years of follow-up Entire follow-up time
Major cardiovascular events N of events = 25 N of events = 38
Fatal cardiovascular events (ICD10 Codes I00-I99) 8b 13b
Non-fatal myocardial infarction (MI)a 14 21
Ischemic cerebral infarctiona 4 6
Minor cardiovascular events N of events = 31 N of events = 38
Percutaneous transluminal coronary angioplasty (PTCA)a 11 13
Aortocoronary bypass 9 10
Angiographically proven coronary stenosis (CAG) ≥ 50%a 4 5
Transient ischemic attack (TIA)a 6 9
Carotid endarterectomy (CEA)a 1 1

aTwo patients had a TIA (=first event) and an ischemic stroke (=second event), 1 patient had a CAG (=first event) and an ischemic stroke (=second event); 1 patient had a PTCA (=first event) and an ischemic stroke (=second event); 1 patient had a CEA (=first event) and a MI (=second event) and 1 patient had a TIA (=first event) and a MI (=second event): n = 6. In these patients, the first event was included in the minor and the second event in the major composite cardiovascular endpoint, respectively. bTwo patients (one within the first five years) suffered a fatal cardiovascular event and had a non-fatal event before and thus the non-fatal event was considered in the analysis of the major cardiovascular endpoint.