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. 2017 Apr 3;7:45725. doi: 10.1038/srep45725

Figure 4. Effect of TFV and TAF on fibroblast wound healing.

Figure 4

(a) Scratch width measurements were taken to assess wound closure using fibroblasts from EM, CX and ECX from the same patient. Fibroblasts were incubated with TFV (1 mg/ml; 3277 μM) for 24 h before scratch and 24 h and 48 h after scratch. % of wound closure is shown at 24 h and 48 h. The bars represent mean and SEM from triplicate cultures. *p < 0.05. (b) Dose response of TFV and TAF (c) inhibition of uterine fibroblasts wound healing following scratch. Scratch width measurements were determined for EM fibroblasts incubated with increasing concentrations of TFV (b) or TAF (c) for 24 h before scratch and 24 h and 48 h after scratch. Each circle represents a different patient (n = 5 for TVF and n = 4 for TAF). The mean and SEM were shown. *p < 0.05. **p < 0.01.