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. 2017 Apr 3;7:45725. doi: 10.1038/srep45725

Figure 6. Effect of TFV and TAF on acute secretion of chemokines and antimicrobials by polarized epithelial cells.

Figure 6

(a) EM epithelial cells were treated with TFV (1 mg/ml; 3277 μM) or TAF (1 μg/ml; 2 μM), scratched and supernatants collected 3 h later and analyzed for the presence of elafin, HBD2, CCL20 and CXCL5. C: untreated control. Bars represent mean ± SEM from 3 independent experiments with 3 different donors run in triplicates. *p < 0.05. (b) EM epithelial cells treated with low dose of TFV (0.22 mg/ml), scratched and supernatants collected after 3 h. Graph shows fold increase in elafin, HBD2 and CCL20 compared to control (N = 3). *p < 0.05.