Figure 8.

Thickness measurements in horizontal SD-OCT scans of patients analyzed using the segments employed for qAF₈ determinations. (A, B) REC+, Bruch's membrane to the border of the outer plexiform/inner nuclear layer (INL/OPL); OS+, Bruch's membrane to EZ. Thicknesses (mm) are presented as box and whisker plots (horizontal line, median; top and bottom box borders are 25th and 75th percentiles; horizontal lines outside the box are minimum and maximum). In RP patients, small rings were used to measure thicknesses external to the ring; peripheral rings were used to measure thicknesses internal to the inner border of the ring. Outliers (greater than 1.5 SD from the mean) are indicated by filled circles. Thicknesses in RP patients are compared to a database of healthy eyes (healthy). *P < 0.01, compared to healthy eyes. (C–E) Horizontal axis of SD-OCT scan is indicated by arrow in corresponding SW-AF image (C). Measurement areas used for qAF₈ segmental analysis are outlined in SW-AF image (solid white line). Area outlined by dashed rectangle in SW-AF image in C is enlarged in D. Vertical red line in D and E marks the position of thickness measurements acquired at midpoint of the temporal segment. RPE/BM, retinal pigment epithelium/Bruch's membrane.