Figure 1.

Ciliary dynamics and cell-cycle progression. (A) Diagram depicts cell-cycle-dependent ciliary assembly and biphasic resorption. (Figure created from data in Bettencourt-Dias and Carvalho-Santos 2008.) (B) Cartoon in which the cell fate choice of a dividing cortical progenitor depends on the time required for ciliary resorption, and, in turn, G₁ duration. The primary cilium projecting from the apical endfeet of neural progenitor (in turquoise) faces the ventricle and encounters signal gradient(s) from the cerebral spinal fluid (CSF). VZ, Ventricle zone; IZ, intermediate zone; CP cortical plate.