Clock cells, which express the core components of the molecular clock, are depicted on the right. These cells are interconnected and heterogeneous between and within clusters, allowing cells to serve different functions, and respond to different environmental conditions. On the left, two groups of output neurons that do not express the molecular components of the clock, but have cycling neuronal activity and are important for behavioral activity rhythms, suggesting clock input. DN, dorsal neurons; LN, lateral neurons (lLNv, large ventral lateral neurons; sLNv, small ventral lateral neurons; LNd, dorsal lateral neurons); LPN, lateral posterior neurons; LHLK, lateral horn leucokinin neuron; DH44, Diuretic Hormone 44.