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. Author manuscript; available in PMC: 2017 Apr 3.
Published in final edited form as: Dig Dis. 2016 Mar 16;34(1-2):27–34. doi: 10.1159/000442921

Figure 1. IBD risk alleles are found in multiple components of the autophagy pathway.

Figure 1

NOD 2, nucleotide-binding oligomerization domain-containing protein 2; SMURF1, Smad ubiquitination regulatory factor 1; RIP2, receptor-interacting protein 2; NCF4, neutrophil cytosolic factor 4; IRGM, immunity-related GTPase family M; VDR, vitamin D receptor; XBP1, X-box-binding protein 1; NLRP3, NOD-like receptor pyrin domain-containing protein 3; ULK1, unc-51-like kinase complex 1; DAP1, death-associated protein 1; ATG16L1, autophagy-related gene 16 like 1; ATG4, autophagy-related protein 4; MAP1LC3A, microtubule-associated protein 1 light chain 3 alpha; PTPN2, protein tyrosine phosphatase non-receptor type 2; LRRK2, leucine rich repeat kinase 2.