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Effects of inhibition of nestin phosphorylation in pancreatic cancer
| Wild‐type nestin | Thr315 | Thr1299 | Thr315+1299 | |
|---|---|---|---|---|
| Growth | → | ↓ | ↓ | ↓ |
| Migration | ↑ | ↑ | ↑ | → |
| Invasion | ↑ | ↑ | ↑ | → |
Thr315: nestin expression vector mutated at threonine‐315 to suppress phosphorylation; Thr1299: nestin expression vector mutated at threonine‐1299 to suppress phosphorylation; Thr315+1299: nestin expression vector mutated at both threonine‐315 and ‐1299.
