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. 2017 Apr 3;12(4):e0174309. doi: 10.1371/journal.pone.0174309

Fig 3. Knocking-down of CREPT down-regulated cyclin D1 and c-Myc expression in OSCC-derived cell lines.

Fig 3

(A) The cyclin D1 and c-Myc levels in con- or shCREPT-treated cells as determined by Western blotting with β-actin as the loading control. (B) Statistics showed that the amounts of cyclin D1 and c-Myc protein in shCREPT-transfected cells were decreased markedly compared with the con-transfected cells. (*p <0.05, Mann-Whitney U test). (C) Statistics showed that the cyclin D1 and c-Myc protein expression in shCREPT-transfected cells were decreased markedly compared with the con-transfected cells. (*p <0.05, Mann-Whitney U test).