Strategy for initiation of AIP wok-up is based on combined analysis of Ca19-9 level, Eosinophil percentage, Globulin and Hemoglobin level. Elevated eosinophil percentage, globulin level together with decreased hemoglobin level are suggestive of AIP. According to our present study, Ca19-9 < 306.75 u/ml, E%>4.15%, Globulin>29.80 g/L and Hb (M) < 114.5 g/L Or Hb (F) < 118.5 g/L are suggested to be the cut-off value for diagnosis. Abbreviations: AIP, autoimmune pancreatitis; ICDC, International Consensus Diagnostic Criteria for AIP; HISORt, histology, imaging, serology, other organ involvement, response to steroid therapy criteria for autoimmune pancreatitis.