Table 2.
Multivariate Models of the Impact of Age on Extent of CT-defined Functional Small Airway Abnormality (PRMFSA) in Subjects Free of Airflow Obstruction (N = 1,066)*
| β (95% CI) | |
|---|---|
| Demographics | |
| Age (per 10-yr increment) | 2.7 (2.2 to 3.2) |
| Female (vs. male) | −1.1 (−2.3 to 0.1) |
| African American race (vs. non-Hispanic white) | −0.4 (−1.7 to 0.8) |
| Smoking history (per 10 pack-years) | 0.1 (−0.1 to 0.3) |
| Smoking status | |
| Never-smoker | Reference |
| Former smoker | 0.3 (−1.3 to 1.9) |
| Currently smoker | −0.8 (−2.4 to 0.7) |
| History of asthma (vs. no history of asthma) | −0.4 (−1.7 to 0.9) |
Definition of abbreviations: CI = confidence interval; CT = computed tomography; FSA = functional small airway abnormality; PRM = parametric response mapping.
*
The models were additionally adjusted for height, clinical center, and scanner.