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. 2017 Mar 14;5(1):E229–E236. doi: 10.9778/cmajo.20160101

Table 2: Change in aerobic capacity and diet quality.

Month Raw values no.*
(mean ± SD)
Maximum likelihood,†
mean ± SE
Maximum likelihood change from baseline,†
mean
(95% CI)
p value
Age-sex standardized VO2max percentile
0 287
(46.8 ± 24.0)
46.9 ± 1.2
3 238
(59.7 ± 22.4)
60.5 ± 1.1 13.6 
(11.7-15.6)
< 0.0001
12 182
(63.0 ± 20.6)
62.5 ± 1.2 15.6 
(13.3-17.9)
< 0.0001
Canadian Healthy Eating Index (range 0-100)
0 284
(57.9 ± 14.2)
57.9 ± 0.8
3 256
(68.6 ± 12.4)
68.5 ± 0.8 10.6 
(8.8-12.4)
< 0.0001
12 209
(68.0 ± 14.1)
67.5 ± 0.9 9.6 
(7.6-11.6)
< 0.0001
Mediterranean diet score range (0-14)
0 207
(4.7 ± 1.6)
4.8 ± 0.1
3 233
(6.1 ± 2.0)
6.2 ± 0.1 1.4 
(1.1-1.6)
< 0.0001
12 209
(6.2 ± 1.9)
6.2 ± 0.1 1.4 
(1.1-1.6)
< 0.0001

Note: CI = confidence interval, SD = standard deviation, SE = standard error.

*No. of patients where the variable was captured.

†The maximum likelihood mean and change use all available data to estimate the expected values using within patient correlations between outcomes and time points. The maximum likelihood mean is estimated for a 60-year-old assuming even numbers of men and women.