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. 2017 Mar 24;20(1):35–44. doi: 10.4048/jbc.2017.20.1.35

Table 4. Association of microRNA-222 expression levels with expression of epithelial-mesenchymal transition markers according to hormone receptor status.

Marker Hormone receptor-positive subgroup (n = 145) Hormone receptor-negative subgroup (n=52)
miR-222 low, No. (%) miR-222 high, No. (%) p-value* miR-222 low, No. (%) miR-222 high, No. (%) p-value*
Vimentin 0.475 0.004
 Negative 63 (92.6) 74 (96.1) 11 (36.7) 17 (77.3)
 Positive 5 (7.4) 3 (3.9) 19 (63.3) 5 (22.7)
SMA NA 0.161
 Negative 68 (100) 77 (100) 22 (73.3) 20 (90.9)
 Positive 0 0 8 (26.7) 2 (9.1)
Osteonectin 0.371 0.016
 Negative 67 (98.5) 73 (94.8) 20 (66.7) 21 (95.5)
 Positive 1 (1.5) 4 (5.2) 10 (33.3) 1 (4.5)
N-cadherin 0.047 0.442
 Negative 66 (97.1) 68 (88.3) 24 (80/.0) 20 (90.9)
 Positive 2 (2.9) 9 (11.7) 6 (20.0) 2 (9.1)
E-cadherin loss 0.036 0.075
 Negative 54 (80.6) 50 (64.9) 3 (10.0) 7 (31.8)
 Positive 13 (19.4) 27 (35.1) 27 (90.0) 15 (68.2)

miR-222=microRNA-222; SMA=smooth muscle actin; NA=not available.

*p-values were calculated by the chi-square or Fisher exact test.