Table 6. Multivariate analysis by Cox proportional hazard model in hormone receptor-positive subgroup.

Variable	HR	95% CI	p-value
T stage (1 vs. 2–3)	2.238	0.549–9.129	0.261
N stage (0 vs. 1–3)	2.268	0.591–8.704	0.233
Histologic grade (I–II vs. III)	0.675	0.133–3.428	0.635
Lymphovascular invasion (absent vs. present)	1.675	0.429–6.543	0.458
p53 overexpression (absent vs. present)	2.936	0.540–15.950	0.212
Ki-67 index ( < 20% vs. ≥ 20%)	0.994	0.200–4.935	0.994
HER2 (negative vs. positive)	0.239	0.027–2.087	0.195
miR-222 expression level (low vs. high)	5.675	1.082–29.756	0.040

HR=hazard ratio; CI=confidence interval; HER2=human epidermal growth factor receptor 2; miR-222=microRNA-222.