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. Author manuscript; available in PMC: 2018 Apr 1.

Published in final edited form as: J Thromb Haemost. 2017 Feb 25;15(4):802–813. doi: 10.1111/jth.13620

Freshly isolated washed platelets from healthy human donors were treated with vehicle (0.1% DMSO) or maresin 1 for 15 minutes then were either left unactivated (A), or activated with 5 μM ADP (B), or 0.1 U/mL thrombin (C) for 15 minutes. Supernatants were collected and analyzed for mediator release by Luminex Assay. Mean +/− SEM. n=4 Statistical significance was determined by One-Way RM ANOVA with Dunnett’s multiple comparison post-test.

Freshly isolated washed platelets from healthy human donors were treated with vehicle (0.1% DMSO) or maresin 1 for 15 minutes then were either left unactivated (A), or activated with 5 μM ADP (B), or 0.1 U/mL thrombin (C) for 15 minutes. Supernatants were collected and analyzed for mediator release by Luminex Assay. Mean +/− SEM. n=4 Statistical significance was determined by One-Way RM ANOVA with Dunnett’s multiple comparison post-test.

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