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Combined anticancer effect of curcumin pre-treatment and cisplatin on tumor volume (mm3) in breast cancer rats. All the values were expressed as mean ± SEM (n = 8). *P < 0.05, **P < 0.01. a vs. breast cancer control. Where BCC is breast cancer control, CUR is curcumin, CIS is cisplatin, and CUR + CIS is pre-treatment of curcumin (120 mg/kg) for 5 days, followed by single dose of cisplatin (7.5 mg/kg) on the 5th day.
