Table 2.
The combined anticancer effects of curcumin and cisplatin on % tumor inhibition in breast cancer rats.
0th Day | 3rd Day | 6th Day | 9th Day | |
---|---|---|---|---|
BCC | 100 | 178 (+78) | 245 (+145) | 292 (+192) |
CUR | 100 | 93 (−7) | 85 (−15) | 80 (−20) |
CIS | 100 | 88 (−12) | 82 (−18) | 76 (−24) |
CUR + CIS | 100 | 75 (−25) | 57 (−43) | 34 (−66) |
Where BCC is breast cancer control, CUR is curcumin, CIS is cisplatin, and CUR + CIS is pre-treatment of curcumin (120 mg/kg) for 5 days, followed by single dose of cisplatin (7.5 mg/kg) on the 5th day.