Table 2. The empirical bias, sMSE, CP and IL of NO under different genetic model.
MAF | Bias | sMSE | Standard Interval |
Wilson Interval |
Log−Delta Interval |
|||
---|---|---|---|---|---|---|---|---|
CP | IL | CP | IL | CP | IL | |||
Inferring λ2R(=1.97) under the recessive model with β1 = 0.25 | ||||||||
0.15 | 0.0438 | 0.342 | 0.942 | 1.363 | 0.948 | 1.313 | 0.949 | 1.319 |
0.30 | 0.0092 | 0.174 | 0.948 | 0.701 | 0.948 | 0.694 | 0.948 | 0.695 |
0.45 | −0.0201 | 0.135 | 0.948 | 0.528 | 0.945 | 0.525 | 0.945 | 0.525 |
Inferring λ2R(=3.58) under the recessive model with β1 = 0.5 | ||||||||
0.15 | 0.0535 | 0.593 | 0.933 | 2.264 | 0.930 | 2.160 | 0.931 | 2.168 |
0.30 | 0.0458 | 0.314 | 0.946 | 1.225 | 0.946 | 1.208 | 0.946 | 1.210 |
0.45 | 0.0088 | 0.252 | 0.949 | 0.989 | 0.950 | 0.980 | 0.950 | 0.981 |
Inferring λ1A(=1.43) under the additive model with β1 = 0.25 | ||||||||
0.15 | −0.0153 | 0.080 | 0.938 | 0.306 | 0.938 | 0.305 | 0.938 | 0.305 |
0.30 | −0.0029 | 0.062 | 0.954 | 0.249 | 0.954 | 0.249 | 0.954 | 0.249 |
0.45 | −0.0018 | 0.061 | 0.939 | 0.239 | 0.939 | 0.239 | 0.939 | 0.239 |
Inferring λ1A(=1.97) under the additive model with β1 = 0.5 | ||||||||
0.15 | 0.0077 | 0.104 | 0.943 | 0.413 | 0.945 | 0.412 | 0.945 | 0.412 |
0.30 | 0.0055 | 0.089 | 0.946 | 0.352 | 0.945 | 0.351 | 0.945 | 0.351 |
0.45 | −0.0060 | 0.089 | 0.949 | 0.348 | 0.949 | 0.347 | 0.949 | 0.347 |
Inferring λ1D(=1.97) under the dominant model with β1 = 0.25 | ||||||||
0.15 | −0.0033 | 0.128 | 0.935 | 0.492 | 0.933 | 0.490 | 0.933 | 0.490 |
0.30 | 0.0041 | 0.123 | 0.952 | 0.491 | 0.953 | 0.489 | 0.953 | 0.489 |
0.45 | 0.0028 | 0.145 | 0.951 | 0.578 | 0.948 | 0.574 | 0.948 | 0.574 |
Inferring λ1D(=3.58) under the dominant model with β1 = 0.5 | ||||||||
0.15 | 0.0440 | 0.243 | 0.943 | 0.952 | 0.947 | 0.944 | 0.947 | 0.945 |
0.30 | 0.0434 | 0.262 | 0.943 | 1.020 | 0.947 | 1.010 | 0.947 | 1.011 |
0.45 | −0.0165 | 0.321 | 0.940 | 1.248 | 0.937 | 1.230 | 0.937 | 1.232 |