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. 2015 Jul 15;5:12105. doi: 10.1038/srep12105

Table 2. The empirical bias, sMSE, CP and IL of NO under different genetic model.

MAF Bias sMSE Standard Interval
Wilson Interval
Log−Delta Interval
CP IL CP IL CP IL
Inferring λ2R(=1.97) under the recessive model with β1 = 0.25
0.15 0.0438 0.342 0.942 1.363 0.948 1.313 0.949 1.319
0.30 0.0092 0.174 0.948 0.701 0.948 0.694 0.948 0.695
0.45 −0.0201 0.135 0.948 0.528 0.945 0.525 0.945 0.525
Inferring λ2R(=3.58) under the recessive model with β1 = 0.5
0.15 0.0535 0.593 0.933 2.264 0.930 2.160 0.931 2.168
0.30 0.0458 0.314 0.946 1.225 0.946 1.208 0.946 1.210
0.45 0.0088 0.252 0.949 0.989 0.950 0.980 0.950 0.981
Inferring λ1A(=1.43) under the additive model with β1 = 0.25
0.15 −0.0153 0.080 0.938 0.306 0.938 0.305 0.938 0.305
0.30 −0.0029 0.062 0.954 0.249 0.954 0.249 0.954 0.249
0.45 −0.0018 0.061 0.939 0.239 0.939 0.239 0.939 0.239
Inferring λ1A(=1.97) under the additive model with β1 = 0.5
0.15 0.0077 0.104 0.943 0.413 0.945 0.412 0.945 0.412
0.30 0.0055 0.089 0.946 0.352 0.945 0.351 0.945 0.351
0.45 −0.0060 0.089 0.949 0.348 0.949 0.347 0.949 0.347
Inferring λ1D(=1.97) under the dominant model with β1 = 0.25
0.15 −0.0033 0.128 0.935 0.492 0.933 0.490 0.933 0.490
0.30 0.0041 0.123 0.952 0.491 0.953 0.489 0.953 0.489
0.45 0.0028 0.145 0.951 0.578 0.948 0.574 0.948 0.574
Inferring λ1D(=3.58) under the dominant model with β1 = 0.5
0.15 0.0440 0.243 0.943 0.952 0.947 0.944 0.947 0.945
0.30 0.0434 0.262 0.943 1.020 0.947 1.010 0.947 1.011
0.45 −0.0165 0.321 0.940 1.248 0.937 1.230 0.937 1.232