Table 1. Demographic data of left ventricular wall thickness, dimension, volume and systolic function of Wilson’s disease patients and controls.
Patients(n = 21) | controls (n = 20) | ||
Parameters | mean ± SD | mean ± SD | p-value |
Age (years) | 11.04 ± 3 .58 (5–17) | 10.53 ± 2.8 (6–16) | 0.61 |
Gender (male/female) | 11/10 | 9/11 | 0.64 |
Weight (kg) | 38.1 ± 16.04 | 38.1 ± 16.04 | 0.84 |
(14.5–68) | (21.4–67) | ||
Height (cm) | 141.5 ± 20.2 | 141.1 ± 14.2 | 0.93 |
(100–187) | (120–168) | ||
Body surface area (m3) | 1.21 ± 0.33 | 1.22 ± 0.25 | 0.92 |
(0.63–1.91) | (0.9–1.72) | ||
Age of diagnosis | 9 ± 2.24 | - | - |
(5–13) | |||
IVSd (mm) | 7.14 ± 1.10 | 6.45 ± 1.39 | 0.85 |
IVSs (mm) | 10.76 ± 1.78 | 9.7 ± 1.65 | 0.56 |
LPWDd (mm) | 5.42 ± 1.16 | 5.2 ± 1.36 | 0.56 |
LPWDs (mm) | 9.52 ± 2.11 | 8.8 ± 1.28 | 0.1 |
LVIDd (mm) | 41.6 ± 6.81 | 42.1 ± 4.52 | 0.79 |
LVEDd/m2 (mm/m2) | 35.5 ± 8.45 | 35.2 ± 5.16 | 0.92 |
LVEDs (mm) | 24.8 ± 4.65 | 26.5 ± 6.09 | 0.32 |
LVEDs/m2 (mm/m2) | 21.05 ± 5.08 | 22.19 ± 4.68 | 0.46 |
EDV (ml) | 83.38 ± 28.76 | 79.8 ± 20.41 | 0.65 |
ESV (ml ) | 24.28 ± 11.89 | 29.5 ± 20.79 | 0.32 |
SV (ml) | 60.85 ± 20.53 | 55.80 ± 13.65 | 0.36 |
CI (ml/min) | 4.60 ± 1.32 | 3.98 ± 0.78 | 0.077 |
EF (%) | 71.76 ± 6.51 | 69.90 ± 5.33 | 0.32 |
FS (%) | 40.9 ± 5.62 | 39.1 ± 4.54 | 0.26 |
EDV: end-diastolic volume, ESV: end-systolic volume, SV: stroke volume, CI: cardiac index, EF: ejection fraction, FS: fractional shortening, CI: cardiac index.