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. 2016 Mar;356(3):549–562. doi: 10.1124/jpet.115.230011

TABLE 2.

Effect of a T6'S mutation on inhibitor pIC50 values

Agonist ΔpEC50 P (H0: ΔpEC50=0) pEC50a
5-HT 0.35 ± 0.07 3 × 10−6 6.00 ± 0.08
Inhibitorb
 Citral −0.36 ± 0.10 0.002 3.55 ± 0.11
 Eucalyptol −0.45 ± 0.22 0.046 3.14 ± 0.05
 Linalool −0.34 ± 0.04 5 × 10−7 3.51 ± 0.24
a

Standard errors were calculated from the errors of the pEC50/pIC50 and ΔpEC50/ΔpIC50 values using propagation of error calculations.

b

There was no significant difference between the ΔpIC50 values for the three inhibitors (P = 0.87).