Skip to main content
. 2017 Mar 23;7:45119. doi: 10.1038/srep45119

Table 5. Associations of the diplotypes and serum lipid phenotypes in the Jing and Han populations.

Diplotype Group TC (mmol/L)1 TG (mmol/L)2 HDL-C (mmol/L) LDL-C (mmol/L) ApoA1 (g/L) ApoB (g/L) ApoA1/ApoB
TT-AA Jing
Carrier 5.28 ± 0.92 1.50 (1.17) 1.81 ± 0.48 2.85 ± 0.42 1.32 ± 0.26 1.06 ± 0.25 1.31 ± 0.38
Non-carrier 5.31 ± 0.85 1.55 (1.24) 1.79 ± 0.43 2.85 ± 0.46 1.28 ± 0.22 1.09 ± 0.25 1.24 ± 0.38
F 0.315 −2.342 0.954 0.063 8.591 7.766 14.934
P 0.575 0.019 0.329 0.801 0.003 0.005 0.000
Han
Carrier 4.99 ± 0.89 1.36 (1.07) 1.75 ± 0.57 2.86 ± 0.43 1.33 ± 0.20 1.04 ± 0.24 1.34 ± 0.39
Non-carrier 4.97 ± 0.84 1.46 (1.12) 1.80 ± 0.50 2.87 ± 0.42 1.33 ± 0.20 1.05 ± 0.23 1.33 ± 0.36
F 0.339 −2.130 0.214 0.062 0.022 0.468 1.332
P 0.560 0.033 0.644 0.803 0.882 0.494 0.249
TT-AC Jing
Carrier 5.30 ± 0.86 1.54 (1.23) 1.80 ± 0.44 2.82 ± 0.46 1.28 ± 0.22 1.08 ± 0.25 1.25 ± 0.37
Non-carrier 5.29 ± 0.91 1.51 (1.17) 1.81 ± 0.47 2.86 ± 0.42 1.32 ± 0.26 1.06 ± 0.25 1.30 ± 0.39
F 0.042 −1.257 0.014 2.643 4.011 2.115 5.903
P 0.837 0.209 0.906 0.104 0.045 0.146 0.015
Han
Carrier 4.98 ± 0.85 1.46 (1.10) 1.81 ± 0.51 2.86 ± 0.42 1.34 ± 0.20 1.04 ± 0.23 1.35 ± 0.36
Non-carrier 4.99 ± 0.88 1.37 (1.09) 1.75 ± 0.56 2.87 ± 0.43 1.32 ± 0.20 1.05 ± 0.24 1.33 ± 0.38
F 0.025 −0.738 0.362 0.003 0.758 0.011 0.000
P 0.873 0.461 0.547 0.959 0.384 0.917 0.984
TT-CC Jing
Carrier 5.55 ± 0.93 2.00 (1.84) 1.41 ± 0.24 3.05 ± 0.39 1.20 ± 0.11 1.28 ± 0.14 0.95 ± 0.16
Non-carrier 5.29 ± 0.89 1.51 (1.17) 1.81 ± 0.46 2.85 ± 0.43 1.31 ± 0.25 1.07 ± 0.25 1.29 ± 0.38
F 0.978 −2.935 5.460 1.522 1.697 4.631 5.013
P 0.323 0.003 0.020 0.218 0.193 0.032 0.025
Han
Carrier 4.92 ± 0.82 1.49 (1.19) 1.68 ± 0.41 2.90 ± 0.45 1.26 ± 0.18 1.09 ± 0.21 1.20 ± 0.32
Non-carrier 4.99 ± 0.87 1.37 (1.09) 1.77 ± 0.55 2.87 ± 0.43 1.33 ± 0.20 1.04 ± 0.24 1.34 ± 0.38
F 1.419 −1.756 0.850 0.018 5.181 0.554 4.185
P 0.234 0.079 0.357 0.893 0.023 0.457 0.041
CT/CC-AA Jing
Carrier 5.47 ± 0.61 2.01 (1.70) 1.47 ± 0.44 2.99 ± 0.31 1.14 ± 0.17 1.16 ± 0.21 1.01 ± 0.20
Non-carrier 5.29 ± 0.89 1.51 (1.17) 1.81 ± 0.46 2.85 ± 0.44 1.31 ± 0.25 1.07 ± 0.25 1.29 ± 0.38
F 0.316 −2.625 2.562 0.687 3.774 0.284 2.952
P 0.574 0.009 0.110 0.407 0.052 0.594 0.086
Han
Carrier 5.26 ± 0.73 1.97 (1.71) 1.80 ± 0.52 3.05 ± 0.33 1.36 ± 0.27 1.20 ± 0.23 1.18 ± 0.43
Non-carrier 4.98 ± 0.87 1.36 (1.09) 1.76 ± 0.54 2.87 ± 0.43 1.33 ± 0.20 1.04 ± 0.24 1.34 ± 0.38
F 0.183 −2.938 0.005 0.704 0.701 3.237 0.822
P 0.669 0.003 0.942 0.401 0.403 0.072 0.365
CT/CC-AC Jing
Carrier 5.00 ± 1.16 1.63 (1.56) 1.60 ± 0.49 2.68 ± 0.62 1.24 ± 0.19 1.10 ± 0.21 1.15 ± 0.22
Non-carrier 5.29 ± 0.89 1.51 (1.18) 1.80 ± 0.46 2.85 ± 0.43 1.31 ± 0.25 1.07 ± 0.25 1.29 ± 0.38
F 0.992 −0.678 2.302 0.547 0.571 0.047 0.793
P 0.319 0.497 0.129 0.460 0.450 0.829 0.373
Han
Carrier 5.00 ± 0.80 1.49 (1.20) 1.87 ± 0.49 2.89 ± 0.46 1.32 ± 0.19 1.05 ± 0.25 1.32 ± 0.31
Non-carrier 4.99 ± 0.87 1.37 (1.09) 1.76 ± 0.54 2.87 ± 0.43 1.33 ± 0.20 1.05 ± 0.24 1.34 ± 0.38
F 0.319 −1.747 0.457 0.375 0.395 0.000 0.288
P 0.572 0.081 0.499 0.540 0.530 0.983 0.592
CT/CC-CC Jing
Carrier 5.34 ± 0.78 1.51 (1.17) 1.81 ± 0.40 2.96 ± 0.42 1.29 ± 0.23 1.11 ± 0.27 1.24 ± 0.44
Non-carrier 5.29 ± 0.90 1.52 (1.18) 1.80 ± 0.46 2.84 ± 0.44 1.31 ± 0.25 1.07 ± 0.25 1.29 ± 0.38
F 0.295 −0.558 0.662 6.095 1.038 4.974 3.763
P 0.587 0.577 0.416 0.014 0.308 0.026 0.053
Han
Carrier 4.52 ± 0.61 1.04 (0.93) 1.85 ± 0.23 2.81 ± 0.36 1.36 ± 0.16 1.08 ± 0.20 1.30 ± 0.24
Non-carrier 4.99 ± 0.87 1.37 (1.10) 1.76 ± 0.54 2.87 ± 0.43 1.33 ± 0.20 1.05 ± 0.24 1.34 ± 0.38
F 2.334 −1.955 0.018 0.342 0.007 0.015 0.094
P 0.127 0.051 0.893 0.559 0.933 0.903 0.760

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; ApoA1/ApoB, the ratio of apolipoprotein A1 to apolipoprotein B. 1Mean ± SD determined by the ANCOVA. 2Median (interquartile range) tested by the Wilcoxon-Mann-Whitney test. A P-value less than 0.025 was considered statistically significant after the Bonferroni correction.