Table 6. Association of the variants, haplotypes and diplotypes of the CAPN3 and FRMD5 and serum lipid variables.
| Lipid variable | Gene | Type | Beta | Std.error | Chi-square | P-value |
|---|---|---|---|---|---|---|
| Jing | ||||||
| HDL-C | FRMD5 | Genotype | −0.359 | 0.150 | 5.727 | 0.017 |
| HDL-C | CAPN3-FRMD5 | Diplotype | 0.535 | 0.235 | 5.191 | 0.023 |
| LDL-C | CAPN3 | Genotype | 0.059 | 0.046 | 2.410 | 0.016 |
| ApoA1 | FRMD5 | Genotype | −0.063 | 0.010 | −2.628 | 0.009 |
| ApoA1 | CAPN3-FRMD5 | Haplotype | 0.159 | 0.075 | 4.555 | 0.033 |
| ApoB | FRMD5 | Genotype | 0.079 | 0.010 | 3.301 | 0.001 |
| ApoA1/ApoB | FRMD5 | Genotype | −0.096 | 0.015 | −4.070 | 0.000 |
| ApoA1/ApoB | CAPN3-FRMD5 | Diplotype | 0.414 | 0.201 | 4.236 | 0.040 |
There was no significantly association in the Han population.