Figure 7. ABC protects from oxidative stress and apoptosis in vivo in Aβ25–35-injected animals.
(a) Decrease in oxidative stress assessed by lipid peroxidation in mice hippocampi following ABC treatment (n = 6). (b) cPARP levels were normalised by ABC in mice hippocampi (n = 6). A higher efficacy was observed for ABC with respect to its single drugs. ABC was composed of ACP 0.2 mg Kg−1 and BCL 3 mg Kg−1. Values are mean ± s.e.m. ***P < 0.001 versus Aβ; ANOVA with Dunnett's test. CHP: cumene hydroperoxyde; Sc.: scrambled.