Skip to main content
. 2015 Jan 7;5:7656. doi: 10.1038/srep07656

Figure 1. Leader cells play a crucial role in collective migration of MDCK cells.

Figure 1

(a) MDCK cells moving collectively as directed by a leader cell. The migratory direction of each cell is shown by colored dots. (b) The direction of the follower cells moving after removal of the leader cell at 0 h. (a and b) Scale bar: 100 μm. (c) Quantification of migration direction (N = 3). In each experiment, 20 follower cells were manually tracked. L(+): before and L(−): after a leader was killed. P < 0.01 by Watson's two-sample test of homogeneity. (d) Quantification of migratory velocity. **P < 0.01 by Student's t-test. The mean value ± S.D.