Table 1.
Phenotype metabolising classes based on CYP2C19 genotype∗.
| Phenotype | Examples of the genotype | Enzyme activity |
|---|---|---|
| Ultrarapid metabolizer (UM) | ∗1/∗17 | Normal or increased enzyme activity |
| ∗17/∗17 | ||
|
| ||
| Extensive metabolizer (EM) | ∗1/∗1 | Normal enzyme activity |
|
| ||
| Intermediate metabolizer (IM) | ∗1/∗2 | Intermediate enzyme activity |
| ∗1/∗3 | ||
| ∗2/∗17 | ||
|
| ||
| Poor metabolizer (PM) | ∗2/∗2 | Low or absent enzyme activity |
| ∗3/∗3 | ||
| ∗2/∗3 | ||
∗This table is adapted and modified with permission from the publisher. Original source: Scott et al. (2013) [10]. Copyright© (2013). Published by Wiley. All rights reserved.