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. 2017 Mar 30;8:14893. doi: 10.1038/ncomms14893

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Copyright © 2017, The Author(s)

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(a) Schematic representation of mammalian TSPO embedded into liposomes. Cholesterol is marked in red and cyan, the TSPO-ligand DAA1106 in orange/yellow. (b) CD spectrum of the membrane-embedded mTSPO/DAA1106 complex. (c) High-resolution ¹³C–¹³C proton-driven spin diffusion spectrum of mTSPO bound to DAA1106. (d) Secondary structure analysis of liposome-embedded mTSPO in complex with DAA1106. Positive δC^α-δC^β values are indicative of α-helix and identify five transmembrane helices and a short cytosolic helix following transmembrane helix I.