Table 4. Schematics of prediction of breast cancer phenotypes from Kepmean+ADCmean+SUVmax.
Predicted |
Leave-one-out cross validation |
|||||||
---|---|---|---|---|---|---|---|---|
HER2 enriched | Luminal A | Luminal B | Luminal HER2 | HER2 enriched | Luminal A | Luminal B | Luminal HER2 | |
Results on biopsy Only | ||||||||
Observed | ||||||||
HER2 enriched | 5 | 0 | 0 | 2 | 4 | 0 | 0 | 3 |
Luminal A | 0 | 2 | 1 | 0 | 0 | 0 | 3 | 0 |
Luminal B | 1 | 0 | 6 | 1 | 1 | 2 | 4 | 1 |
Luminal HER2 | 1 | 0 | 1 | 1 | 1 | 0 | 2 | 0 |
14/21 (67%); P=0.004 |
8/21 (38%); P=0.22 |
|||||||
Results on mastectomy in 16 cases plus biopsy in 5 cases | ||||||||
Observed | ||||||||
HER2 enriched | 6 | 0 | 0 | 1 | 5 | 0 | 0 | 2 |
Luminal A | 1 | 5 | 0 | 0 | 1 | 4 | 1 | 0 |
Luminal B | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 |
Luminal HER2 | 1 | 0 | 1 | 1 | 1 | 0 | 2 | 0 |
13/21 (62%); P=0.001 | 10/21 (48%); P=0.04 |
Abbreviations: ADC=apparent diffusion coefficient; HER2=human epidermal growth factor receptor 2.