Table 2. All analytes.
| Blood test | Cases Mean | Controls Mean | RR (high-risk quintile vs low-risk quintile) | P-value (t-test) |
|---|---|---|---|---|
|
Females | ||||
| Haematology | ||||
| Basophils | 0.03 | 0.03 | 1.19 (1.02–1.48) | 0.0003 |
| Eosinophils | 0.21 | 0.18 | 2.03 (1.58–2.79) | <0.0001 |
| Haemoglobin | 11.8 | 13.02 | 5.69 (4.31–7.97) | <0.0001 |
| Lymphocytes | 2.25 | 2.21 | 1.37 (1.06–1.78) | 0.43 |
| Mean corpuscular volume | 84.50 | 88.64 | 3.52 (2.84–4.39) | <0.0001 |
| Monocytes | 0.56 | 0.51 | 1.99 (1.63–2.65) | <0.0001 |
| Mean platelet volume | 10.78 | 11.06 | 2.33 (1.72–3.26) | <0.0001 |
| Neutrophils | 4.33 | 3.70 | 3.02 (2.42–4.17) | <0.0001 |
| Platelets | 301 | 254 | 3.87 (3.09–5.21) | <0.0001 |
| Red blood cell count | 4.39 | 4.48 | 1.97 (1.51–2.61) | <0.0001 |
| Red blood cell distribution width | 14.81 | 13.71 | 4.54 (3.58–6.26) | <0.0001 |
| White blood cell count | 7.46 | 6.65 | 2.17 (1.66–3.02) | <0.0001 |
| Liver function | ||||
| Alkaline phosphatase | 92.37 | 76.39 | 2.43 (1.75–3.33) | <0.0001 |
| Alanine aminotransferase | 18.94 | 21.91 | 3.12 (2.45–4.2) | <0.0001 |
| Aspartate aminotransferase | 21.23 | 22.64 | 2.45 (1.82–3.2) | 0.011 |
| Bilirubin | 0.52 | 0.60 | 2.31 (1.71–3.25) | <0.0001 |
| γ-Glutamyl transferase | 58.76 | 38.35 | 1.42 (1.04–2.15) | 0.10 |
| Metabolic | ||||
| Albumin | 4.08 | 4.22 | 2.62 (1.91–3.44) | <0.0001 |
| Cholesterol | 201 | 210 | 1.77 (1.29–2.39) | <0.0001 |
| Glucose | 110 | 109 | 1.2 (1.03–1.74) | 0.28 |
| Haemoglobin A1c | 6.57 | 6.65 | 1.06 (1–1.75) | 0.16 |
| Lactic acid dehydrogenase | 375 | 351 | 1.32 (1.04–2.57) | 0.17 |
| Low-density lipoprotein | 121 | 126 | 1.4 (1.09–1.86) | 0.00082 |
| Protein | 7.11 | 7.28 | 2.12 (1.54–3.08) | <0.0001 |
| Prothrombin time (%) | 15.00 | 15.47 | 4.58 (2.97–8) | 0.44 |
| Partial thromboplastin time | 25.97 | 27.19 | 1.75 (1.06–4.13) | 0.00016 |
| Other | ||||
| Fe – iron | 46.84 | 77.22 | 16 (9.14–33.4) | <0.0001 |
| Ferritin | 46.24 | 69.62 | 4.59 (3.06–7.73) | <0.0001 |
| Vitamins | ||||
| Folic acid | 4.33 | 4.43 | 1.91 (1.28–2.96) | 0.37 |
| Vitamin B12 | 430 | 426 | 1.07 (1–1.54) | 0.40 |
|
Males | ||||
| Haematology | ||||
| Basophils | 0.03 | 0.03 | 1.4 (1.14–1.75) | 0.0017 |
| Eosinophils | 0.25 | 0.22 | 1.62 (1.29–2.04) | <0.0001 |
| Haemoglobin | 13.3 | 14.43 | 3.77 (2.66–5.08) | <0.0001 |
| Lymphocytes | 2.13 | 2.21 | 1.17 (1.01–1.53) | 0.026 |
| Mean corpuscular volume | 85.7 | 88.90 | 3.44 (2.7–4.87) | <0.0001 |
| Monocytes | 0.68 | 0.61 | 2.11 (1.74–2.8) | <0.0001 |
| Mean platelet volume | 10.78 | 11.07 | 2.33 (1.8–2.93) | <0.0001 |
| Neutrophils | 4.69 | 4.13 | 2.29 (1.73–2.96) | <0.0001 |
| Platelets | 261 | 222 | 3.78 (2.95–4.88) | <0.0001 |
| Red blood cell count | 4.76 | 4.87 | 1.75 (1.45–2.24) | <0.0001 |
| Red blood cell distribution width | 14.26 | 13.61 | 2.87 (2.23–3.78) | <0.0001 |
| White blood cell count | 7.79 | 7.20 | 2.31 (1.87–3.05) | <0.0001 |
| Liver function | ||||
| Alkaline phosphatase | 86 | 73.36 | 2.76 (2.21–3.88) | <0.0001 |
| Alanine aminotransferase | 20.97 | 25.61 | 3.61 (2.69–4.72) | <0.0001 |
| Aspartate aminotransferase | 21.19 | 23.77 | 2.75 (2.17–3.88) | <0.0001 |
| Bilirubin | 0.63 | 0.74 | 2.71 (1.9–3.72) | <0.0001 |
| γ-Glutamyl transferase | 59.73 | 45.92 | 1.29 (1.02–2.03) | 0.026 |
| Metabolic | ||||
| Albumin | 4.19 | 4.30 | 1.97 (1.5–2.55) | <0.0001 |
| Cholesterol | 184 | 189.48 | 1.46 (1.1–1.9) | 0.00038 |
| Glucose | 112 | 114 | 1.13 (1–1.43) | 0.046 |
| Haemoglobin A1c | 6.76 | 6.74 | 1.07 (1–1.67) | 0.40 |
| Lactic acid dehydrogenase | 332 | 341 | 1.64 (1.05–3.57) | 0.24 |
| Low-density lipoprotein | 113 | 116 | 1.28 (1.02–1.55) | 0.044 |
| Protein | 7.20 | 7.30 | 2.62 (1.81–3.58) | 0.00034 |
| Prothrombin time (%) | 21.32 | 22.63 | 3 (2.07–4.67) | 0.33 |
| Partial thromboplastin time | 27.85 | 28.55 | 1.61 (1.04–3.17) | 0.079 |
| Other | ||||
| Fe – iron | 54.68 | 84.35 | 5.38 (3.36–9.08) | <0.0001 |
| Ferritin | 73.53 | 124.84 | 4.95 (3.22–8.45) | <0.0001 |
| Vitamins | ||||
| Folic acid | 4.42 | 4.46 | 1.53 (1.06–2.52) | 0.44 |
| Vitamin B12 | 381 | 393 | 1.39 (1.02–2.5) | 0.16 |
Abbreviation: RR=risk ratio.