Figure 1. Absence of age-dependent nigrostriatal pathway neurodegeneration in wild-type Octodon degus.
(A) Representative photomicrographs of striatal tyrosine hydroxylase (TH) immunostaining in sagittal section of octodons. In the lower panel, Green fire blue LUT (lookup table) was applied to scanned section to enhance contrast and highlight the absence of difference between groups. (B) No significant decrease of mean grey values of striatal TH immunoreactivity [F(3,11) = 3.561, p = 0.0509]. (C,D) TH immunoblot levels in midbrain protein homogenates from octodons at different ages. Scale bar: 1 mm.