Table 2. Functional annotations of BIRC5 module based on pathway enrichment analysis.
| Gene set | Size | Overlap | FDR | BIRC5 module gene names in Gene set |
|---|---|---|---|---|
| Mitotic M-M/G1 phases | 222 | 16 | P < 5.0e-4 | AURKB, SPC25, CDCA8, CENPA, INCENP, CENPN, CKAP5, SGOL2, SGOL1, CENPP, BIRC5, NDC80, CENPK, SMC2, SMC4, CENPH |
| Aurora B signaling | 40 | 13 | p < 5.0e-4 | AURKB, NCAPH, CDCA8, CENPA, NCAPG, INCENP, NSUN2, SGOL1, BIRC5, NDC80, SMC2, SMC4, NCAPD2 |
| Chromosome Maintenance | 105 | 8 | p < 3.3e-4 | RSF1, HJURP, CENPA, OIP5, CENPN, CENPP, CENPK, CENPH |
| Aurora A signaling | 31 | 4 | p < 2.5e-4 | AURKB,CENPA,CKAP5,BIRC5 |