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. 2017 Apr 4;7:45663. doi: 10.1038/srep45663

Figure 4.

Figure 4

(A) 2D model developed in COMSOL. Schematic of the model created in COMSOL defining the boundary conditions of the external medium. Electric field is considered from left to right aligned with the x-axis direction. (B) Creation of membrane pores with induced transmembrane voltage. (a) The ITV profile along the membrane at two different times of the simulation (b) Cell membrane pore density over the simulation time. (C) Conductivity, permeability and electro-diffusion characteristics observed under 10 ms electric pulse of an external field. (a) Conductivity of the cell membrane, which reach to a maximum value of 2.36 × 10−5 S/m, before the pulse ceases (b) Permeability of the cell membrane also follow the same exponential trend to decrease over time after the pulse was turned off (c) Time course of electro-diffusion coefficient of the cell membrane.