Table 1. Effects of sesamol treatment on the bioenergetic parameters in HepG2 cells.
| Oxygen consumption rates (pmol/min) | ||||
|---|---|---|---|---|
| Control | sesamol | rapamycin | sesamol + rapamycin | |
| Basal respiration | 175 ± 4 | 152 ± 12* | 193 ± 5** | 162 ± 10 |
| OXPHOS-induced respiration | 148 ± 4 | 133 ± 12 | 162 ± 5** | 136 ± 10 |
| H+ leak-induced respiration | 26 ± 10 | 19 ± 5 | 30 ± 9 | 26 ± 6 |
| Maximal respiratory capacity | 365 ± 10 | 317 ± 11** | 410 ± 3** | 378 ± 33## |
| Nonmitochondrial respiration | 75 ± 9 | 83 ± 12 | 85 ± 2 | 87 ± 6 |
| Reserve capacity | 190 ± 10 | 165 ± 11 | 217 ± 3 | 216 ± 33 |
Assay conditions as described in the Methods and Materials. *p ≤ 0.05, **p ≤ 0.01 versus control group. ##p ≤ 0.01 versus Sesamol group.