Table 2.
Differential Pathway Enrichment in FF samples
| Gene Set Name | # Genes Overlap | p-value | FDR q-value |
|---|---|---|---|
| Cellular Compartment C5 | |||
| Cytoplasm | 391 | 1.77E-128 | 4.13E-126 |
| Cytoplasmic part | 265 | 8.87E-90 | 1.03E-87 |
| Organelle part | 228 | 2.04E-76 | 1.59E-74 |
| Intracellular organelle part | 227 | 4.69E-76 | 2.73E-74 |
| Nucleus | 243 | 3.58E-71 | 1.67E-69 |
| Macromolecular complex | 193 | 9.82E-70 | 3.81E-68 |
| Mitochondrion | 101 | 3.55E-52 | 1.18E-50 |
| Protein complex | 150 | 3.96E-48 | 1.15E-46 |
| Membrane | 240 | 1.92E-42 | 4.97E-41 |
| Mitochondrial part | 55 | 4.45E-36 | 1.04E-34 |
| Canonical Pathways C2 | |||
| Huntingtons disease | 71 | 7.32E-46 | 6.52E-43 |
| TCA cycle and electron transport | 63 | 9.81E-46 | 6.52E-43 |
| Alzheimers disease | 67 | 1.96E-44 | 6.53E-42 |
| Adaptive immune system | 116 | 1.96E-44 | 6.53E-42 |
| Immune system | 155 | 5.67E-44 | 1.51E-41 |
| Oxidative phosphorylation | 60 | 1.88E-43 | 4.17E-41 |
| Parkinsons disease | 59 | 1.08E-42 | 2.06E-40 |
| Metabolism of proteins | 111 | 2.29E-42 | 3.81E-40 |
| Respiratory electron transport | 50 | 3.40E-40 | 5.02E-38 |
| Metabolism of RAN | 83 | 2.13E-37 | 2.83E-35 |