Table 3.
Differential Pathway Enrichment in FFPE samples
| Gene Set Name | # Genes Overlap | p-value | FDR q-value |
|---|---|---|---|
| Cellular Compartment C5 | |||
| Plasma membrane | 197 | 6.62E-61 | 1.03E-57 |
| Membrane | 234 | 3.30E-59 | 2.58E-56 |
| Plasma membrane part | 173 | 2.36E-58 | 1.23E-55 |
| Membrane part | 202 | 5.71E-53 | 2.23E-50 |
| Intrinsic to membrane | 177 | 2.20E-51 | 6.87E-49 |
| Intrinsic to plasma membrane | 150 | 2.82E-51 | 7.35E-49 |
| Integral to membrane | 173 | 1.24E-49 | 2.78E-47 |
| Integral to plasma membrane | 146 | 3.29E-49 | 6.43E-47 |
| Neuroactive ligand receptor | 55 | 1.12E-25 | 1.95E-23 |
| Canonical Pathways C2 | |||
| Naba matrisome | 97 | 6.19E-18 | 9.67E-16 |
| Neuroactive ligand receptor | 55 | 1.12E-25 | 1.49E-22 |
| Matrisome | 97 | 6.19E-18 | 4.11E-15 |
| Signaling by GPCR | 85 | 2.44E-15 | 9.19E-13 |
| GPCR downstream signaling | 78 | 2.76E-15 | 9.19E-13 |
| Neuronal system | 42 | 4.12E-15 | 1.10E-12 |
| Transmembrane transport | 51 | 1.89E-14 | 4.20E-12 |
| Matrisome associated | 71 | 1.87E-13 | 3.55E-11 |
| Calcium signaling pathway | 31 | 3.00E-13 | 4.98E-11 |
| Transmission chemical synapses | 28 | 1.48E-10 | 2.18E-08 |
| GPCR ligand binding | 43 | 3.61E-10 | 4.80E-08 |