Table 4. Multivariate analysis for the predictors of the 7 cognitive performance tests at 3 months (stepwise method).
| Predictors | STROOP |
|||
|---|---|---|---|---|
| R2 | Unstandardized Beta | 95% CI | P value | |
| 25 (OH)D (Sufficient Y/N) | 0.26 | 2.06 | −3.05: 7.17 | 0.42 |
| Anxiety score | −7.44 | −11.46: −3.42 | <0.0001 | |
| Age | −0.24 | −0.45: −0.02 | <0.0001 | |
| SDMT | ||||
| 25 (OH)D (Sufficient Y/N) | 0.39 | −5.79 | −12.52: 0.94 | 0.09 |
| Education: college | 14.54 | 6.18: 22.90 | 0.001 | |
| Age | −0.35 | −0.65: −0.05 | 0.02 | |
| Alcohol | 7.92 | 0.51: 15.32 | 0.04 | |
| BVMT T1 | ||||
| 25 (OH)D (Sufficient Y/N) | 0.21 | 0.01 | −1.43: 1.45 | 0.99 |
| Alcohol | 1.83 | 0.26: 3.41 | 0.02 | |
| EDSS | −0.99 | −1.85: −0.14 | 0.02 | |
| BVMT T2 | ||||
| 25 (OH)D (Sufficient Y/N) | 0.27 | −1.69 | −3.18: −0.20 | 0.03 |
| Score leisure activities | 4.90 | 1.89: 7.92 | 0.002 | |
| Age | −0.10 | −0.17: −0.04 | 0.002 | |
| BVMT T3 | ||||
| 25 (OH)D (Sufficient Y/N) | 0.23 | −0.73 | −2.15: 0.69 | 0.31 |
| Age | −0.14 | −0.20: −0.09 | <0.0001 | |
| BVMT-Total Score | ||||
| 25 (OH)D (Sufficient Y/N) | 0.48 | −0.17 | −4.57: 4.22 | .936 |
| EDSS | −2.55 | −5.01:−0.093 | 0.042 | |
| Education: College | 4.377 | 0.658: 8.09 | ||
| Score leisure activities | 9.36 | 1.09: 17.637 | 0.022 | |
| Alcohol | 4.78 | 0.63: 9.49 | 0.047 | |
| MOCA | ||||
| 25 (OH)D (Sufficient Y/N) | 0.31 | −0.71 | −2.22: 0.81 | 0.36 |
| Education: College | 3.90 | 2.05: 5.76 | < 0.0001 | |
| EDSS | −0.91 | −1.79: −0.03 | 0.04 | |
Variables entered in all models are: 25 (OH)D (Sufficient Y/N), Disease duration, EDSS, Age, Education: college, Education: high school, Physical activity, smoking, alcohol, score leisure activities, Anxiety score at baseline, Depression score at baseline, Total Hopkins score at baseline. Abbreviations: MoCA = Montreal Cognitive Assessment; SDMT = Symbol Digit Modalities Test; BVMT-R = Brief Visuospatial Memory test.