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. 2017 Apr 4;17:191. doi: 10.1186/s12906-017-1698-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Carrageenan was injected into the hind paw to produce thermal hyperalgesia in rats. The BuOH fraction (BuOH fr.) at the oral dose of 120 mg/kg significantly increased Δ withdrawal latency, inhibiting the inflammatory hyperalgesia response after 3 h of the treatment. Indomethacin (10 mg/kg) was used as a reference compound. Values are expressed in mean ± SEM from 8 animals per group. * p < 0.05, **p < 0.01 vs. hyperuricemic rats (control)