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. 2017 Apr 4;16:43. doi: 10.1186/s12933-017-0527-5

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Changes in heart rate over time, before and after ischemia, in the four groups (n = 10). The data are presented as the mean ± SD. HR heart rate (bpm). *P < 0.05 vs. G100. ^† P < 0.05 vs. InsG600. ^‡ P < 0.05 vs. G600