Table 3.
Variables | Univariate | P | Multivariatea | P | |||
---|---|---|---|---|---|---|---|
HR | 95% CI | HR | 95% CI | ||||
Multiparous | Yes | 0.32 | 0.15–0.67 | 0.024 | |||
Nulliparous | No | 1 | |||||
Diameter | ≥10 | 0.26 | 0.09–0.70 | 0.0076 | |||
<10 | 1 | ||||||
Histology | Serous | 1 | |||||
Mucinous | 0.41 | 0.18–0.95 | 0.0375 | ||||
Endometrioid | 0.64 | 0.19–2.19 | 0.4808 | ||||
Micropapillary | Yes | 3.88 | 1.76–8.52 | 0.0008 | |||
No | 1 | ||||||
Stage | II & III | 2.55 | 1.10–5.91 | 0.0295 | |||
I | 1 | ||||||
Fertility preserving surgery | |||||||
USO | 1.6 | 0.59–4.33 | 0.3553 | 1.26 | 0.37–4.08 | 0.7395 | |
USO + CC | 5.74 | 2.10–15.67 | 0.0007 | 2.72 | 0.65–11.38 | 0.1719 | |
BC | 5.89 | 2.25–14.42 | 0.0003 | 3.95 | 1.22–12.85 | 0.0223 | |
Radical surgery | 1 | ||||||
Invasive implant | Yes | 4.87 | 1.67–14.20 | 0.0038 | 10.38 | 2.21–48.69 | 0.0030 |
No | 1 | ||||||
Lymphadenectomy | Yes | 0.44 | 0.21–0.94 | 0.0328 | 0.26 | 0.09–0.75 | 0.0129 |
No | 1 | ||||||
Pelvic lymph node metastasis | Yes | 4.34 | 1.21–15.67 | 0.0246 | |||
No | 1 | ||||||
Para-aortic lymph node metastasis | Yes | 17.34 | 1.80–167.50 | 0.0137 | |||
No | 1 | ||||||
Chemotherapy | Yes | 2.72 | 1.20–6.19 | 0.0164 | |||
No | |||||||
Restaging | Yes | 9.8 | 3.96–23.78 | <0.0001 | |||
No |
USO unilateral salpingo-oophorectom, USO + CC unilateral salpingo-oophorectomy plus contralateral cystectomy, BC bilateral cystectomy
aMultivariate model was built after controlling for tumor histology and stage